James D. Harper

Accelerated in vitro fibril formation by a mutant α-synuclein linked to early-onset Parkinson disease

Kelly A. Conway, James D. Harper, Peter T. Lansbury · Nature Medicine · 1998 · 1.5K citations · Full text

Neurodegenerative Diseases, Vitro Fibril Formation, Molecular Biology +6

Fibrils Formed in Vitro from α-Synuclein and Two Mutant Forms Linked to Parkinson's Disease are Typical Amyloid

Kelly A. Conway, James D. Harper, Peter T. Lansbury · Biochemistry · 2000 · 781 citations

Typical Amyloid, Molecular Biology, Mutant Forms +16

Observation of metastable Aβ amyloid protofibrils by atomic force microscopy

James D. Harper, Stanislaus S. Wong, Charles M. Lieber et al. · Chemistry & Biology · 1997 · 692 citations · Full text

Atomic Force Microscopy, Microscopy, Natural Sciences +11

Assembly of Aβ Amyloid Protofibrils:  An in Vitro Model for a Possible Early Event in Alzheimer's Disease

James D. Harper, Stanislaus S. Wong, Charles M. Lieber et al. · Biochemistry · 1999 · 454 citations

Atomic force microscopic imaging of seeded fibril formation and fibril branching by the Alzheimer's disease amyloid-β protein

James D. Harper, Charles M. Lieber, Peter T. Lansbury · Chemistry & Biology · 1997 · 448 citations · Full text

Seeded Fibril Formation, Neurodegenerative Diseases, Alzheimer's Disease +12