Gene–gene interactions in folate and adenosine biosynthesis pathways affect methotrexate efficacy and tolerability in rheumatoid arthritis

Thierry Dervieux, Judith A.M. Wessels, Tahar van der Straaten, Nadia M. Penrod, Jason H. Moore, Henk‐Jan Guchelaar, Joel M. Kremer

Pharmacogenetics and Genomics · 2009 · 56 citations · 40 references

Abstract

These data indicate that gene-gene interactions impact MTX efficacy and tolerability in rheumatoid arthritis.

References

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