Multifactor-Dimensionality Reduction Reveals High-Order Interactions among Estrogen-Metabolism Genes in Sporadic Breast Cancer

Marylyn D. Ritchie, Lance W. Hahn, Nady Roodi, +4

The American Journal of Human Genetics

Breast OncologyEngineeringTumor HeterogeneityComputational BiologyMolecular Biology +9

Cytochrome P450 1B1 (CYP1B1) pharmacogenetics: association of polymorphisms with functional differences in estrogen hydroxylation activity.

Imad H Hanna, Sheila Dawling, Nady Roodi, +2

PubMed

Breast OncologyEstrogen Hydroxylation ActivityGeneticsGenetic EpidemiologyHuman Polymorphism +15

Estrogen Receptor Gene Analysis in Estrogen Receptor-Positive and Receptor-Negative Primary Breast Cancer

Nady Roodi, Lisa Bailey, W Y Kao, +4

JNCI Journal of the National Cancer Institute

Catechol-O-methyltransferase (COMT)-mediated metabolism of catechol estrogens: comparison of wild-type and variant COMT isoforms.

Sheila Dawling, Nady Roodi, Ray Mernaugh, +2

PubMed

Female Reproductive FunctionRedox BiologyOxidative StressCatechol EstrogensSteroid Metabolism +15

Association of cytochrome P450 1B1 (CYP1B1) polymorphism with steroid receptor status in breast cancer.

L R Bailey, Nady Roodi, W.D. Dupont, +1

PubMed

Breast OncologyGeneticsGenetic EpidemiologyHuman PolymorphismPathology +14

Breast cancer and CYPIA1, GSTM1, and GSTT1 polymorphisms: evidence of a lack of association in Caucasians and African Americans.

Lisa Bailey, Nady Roodi, C S Verrier, +3

PubMed

Cancer PathologyGeneticsEpidemiology Of CancerGenetic EpidemiologyHuman Polymorphism +17

Microsatellite instability and loss of heterozygosity in breast cancer.

Cindy J. Yee, Nady Roodi, C S Verrier, +1

PubMed

Breast OncologySomatic VariantCancer PathologyTumor HeterogeneitySomatic Msi +10

Cytochrome P450 1B1–Mediated Estrogen Metabolism Results in Estrogen-Deoxyribonucleoside Adduct Formation

Alexandra R. Belous, David L. Hachey, Sheila Dawling, +2

Cancer Research

Methoxyestrogens exert feedback inhibition on cytochrome P450 1A1 and 1B1.

Sheila Dawling, Nady Roodi, Fritz F. Parl

PubMed

Molecular PharmacologyAldehyde DehydrogenaseBiochemistryMedicineHormonal Receptor +12

High-Mobility Group (HMG) Protein HMG-1 and TATA-Binding Protein-Associated Factor TAF_II30 Affect Estrogen Receptor-Mediated Transcriptional Activation

Carmel S. Verrier, Nady Roodi, Cindy J. Yee, +4

Molecular Endocrinology