Concepedia

A monovalent agonist of TrkA tyrosine kinase receptors can be converted into a bivalent antagonist

Fouad Brahimi, Jing Liu, Andrey Malakhov, Shafinaz F. Chowdhury, Enrico O. Purisima, Ljubica Ivanisevic, Antoine W. Caron, Kevin Burgess, H. Uri Saragovi

Biochimica et Biophysica Acta (BBA) - General Subjects · 2010 · 19 citations · 26 references

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References

26

Structural and Mechanistic Insights into Nerve Growth Factor Interactions with the TrkA and p75 Receptors

Tom S. Wehrman, Xiaolin He, Bill Raab et al. · Neuron · 2007 · 308 citations · Full text

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Gambogic amide, a selective agonist for TrkA receptor that possesses robust neurotrophic activity, prevents neuronal cell death

Sung‐Wuk Jang, Masashi Okada, Iqbal Sayeed et al. · Proceedings of the National Academy of Sciences · 2007 · 163 citations · Full text

, , +17

Minimization of a Polypeptide Hormone

Bing Li, Jeff Y.K. Tom, D. A. OARE et al. · Science · 1995 · 121 citations

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Small Peptide Mimics of Nerve Growth Factor Bind TrkA Receptors and Affect Biological Responses

Lynne LeSauteur, Ling Wei, Bernard F. Gibbs et al. · Journal of Biological Chemistry · 1995 · 110 citations · Full text

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TrkA Immunoglobulin-Like Ligand Binding Domains Inhibit Spontaneous Activation of the Receptor

Juan Carlos Arévalo, Blanca Conde, Barbara L. Hempstead et al. · Molecular and Cellular Biology · 2000 · 109 citations

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