Jing Liu

Oncometabolite 2-Hydroxyglutarate Is a Competitive Inhibitor of α-Ketoglutarate-Dependent Dioxygenases

Wei Xu, Hui Yang, Ying Liu et al. · Cancer Cell · 2011 · 2.8K citations · Full text

Molecular Pharmacology, Aldehyde Dehydrogenase, Biochemistry +4

Deschloroclozapine, a potent and selective chemogenetic actuator enables rapid neuronal and behavioral modulations in mice and monkeys

Yuji Nagai, Naohisa Miyakawa, Hiroyuki Takuwa et al. · Nature Neuroscience · 2020 · 399 citations

Behavioral Modulations, Behavioral Neuroscience, Medicine +13

A Potent, Selective, and Cell-Active Inhibitor of Human Type I Protein Arginine Methyltransferases

Mohammad S. Eram, Yudao Shen, Magdalena M. Szewczyk et al. · ACS Chemical Biology · 2015 · 280 citations · Full text

Drug Target, Epigenetic Change, Molecular Biology +23

In silico design of novel probes for the atypical opioid receptor MRGPRX2

Katherine Lansu, Joel Karpiak, Jing Liu et al. · Nature Chemical Biology · 2017 · 278 citations · Full text

Functional Selectivity, Medicine, Receptor (Biochemistry) +10

Pharmacologic modulation of RNA splicing enhances anti-tumor immunity

Sydney X. Lu, Emma De Neef, James D. Thomas et al. · Cell · 2021 · 267 citations · Full text

Immunology, Rna Splicing, Tumor Immunity +6