Enrico O. Purisima

Small molecule obatoclax (GX15-070) antagonizes MCL-1 and overcomes MCL-1-mediated resistance to apoptosis

Mai Nguyen, Richard Marcellus, Anne Roulston et al. · Proceedings of the National Academy of Sciences · 2007 · 652 citations · Full text

Cancer Research, Elevated Expression, Medicine +13

Solvated Interaction Energy (SIE) for Scoring Protein−Ligand Binding Affinities. 1. Exploring the Parameter Space

Marwen Naïm, Sathesh Bhat, Kathryn N. Rankin et al. · Journal of Chemical Information and Modeling · 2007 · 419 citations

Role of the Occluding Loop in Cathepsin B Activity

Chantal Illy, Omar Quraishi, Jing Wang et al. · Journal of Biological Chemistry · 1997 · 269 citations · Full text

A map of human cancer signaling

Qinghua Cui, Yun Ma, María Jaramillo et al. · Molecular Systems Biology · 2007 · 269 citations · Full text

Identification of high-quality cancer prognostic markers and metastasis network modules

Jie Li, Anne E.G. Lenferink, Yinghai Deng et al. · Nature Communications · 2010 · 262 citations · Full text