Concepedia

TL1A (TNFSF15) Regulates the Development of Chronic Colitis by Modulating Both T-Helper 1 and T-Helper 17 Activation

Hidetoshi Takedatsu, Kathrin S. Michelsen, Bo Wei, Carol J. Landers, Lisa Thomas, Deepti Dhall, Jonathan Braun, Stephan R. Targan

Gastroenterology · 2008 · 249 citations · 37 references

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37

Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

Estelle Bettelli, Yijun Carrier, Wenda Gao et al. · Nature · 2006 · 6.9K citations

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Interleukin 17–producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages

Laurie E. Harrington, Robin D. Hatton, Paul R. Mangan et al. · Nature Immunology · 2005 · 4.7K citations

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IL-23 drives a pathogenic T cell population that induces autoimmune inflammation

Claire L. Langrish, Yi Chen, Wendy M. Blumenschein et al. · The Journal of Experimental Medicine · 2005 · 4K citations · Full text

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TGFβ in the Context of an Inflammatory Cytokine Milieu Supports De Novo Differentiation of IL-17-Producing T Cells

Marc Veldhoen, Richard J. Hocking, Christopher J. Atkins et al. · Immunity · 2006 · 3.6K citations · Full text

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IL-23 is essential for T cell–mediated colitis and promotes inflammation via IL-17 and IL-6

David Yen, Jeanne Cheung, Heleen Scheerens et al. · Journal of Clinical Investigation · 2006 · 1.5K citations · Full text

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