Concepedia

Role of NLRP3 and NLRP1 inflammasomes signaling pathways in pathogenesis of rheumatoid arthritis

Tao Wang, Changliang Zhu, Shuai Wang, Liwen Mo, Guodong Yang, Jun Hu, Fan Zhang

Asian Pacific Journal of Tropical Medicine · 2014 · 24 citations · 12 references

DOIFull text

Open access

Abstract

NLRP3 and NLRP1 inflammasomes signaling pathways are involved in RA inflammatory reaction process as protective factors, and play an important role in RA inflammatory mechanisms.

References

12

The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses

Vijay Rathinam, Zhaozhao Jiang, Stephen N. Waggoner et al. · Nature Immunology · 2010 · 1.3K citations · Full text

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The NLRP3 Inflammasome Protects against Loss of Epithelial Integrity and Mortality during Experimental Colitis

Hasan Zaki, Kelli L. Boyd, Peter Vogel et al. · Immunity · 2010 · 958 citations · Full text

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Type I Interferon Inhibits Interleukin-1 Production and Inflammasome Activation

Greta Guarda, Marion Braun, Francesco Staehli et al. · Immunity · 2011 · 911 citations · Full text

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Colitis induced in mice with dextran sulfate sodium (DSS) is mediated by the NLRP3 inflammasome

Christian Bauer, Peter Duewell, Christine Mayer et al. · Gut · 2010 · 880 citations · Full text

The NLRP3 inflammasome functions as a negative regulator of tumorigenesis during colitis-associated cancer

Irving C. Allen, Erin McElvania, Rita-Marie T. Woodford et al. · The Journal of Experimental Medicine · 2010 · 804 citations · Full text