Concepedia

Nlrp1 Activation

NLRP1 Activation is a molecular signaling event belonging to the class of inflammasome activation processes, distinguished by the specific oligomerization and auto-proteolytic cleavage of the NLRP1 sensor protein in response to pathogenic or cellular stress signals.

176

Publications

15.7K

Citations

1.2K

Authors

403

Institutions

Publications per year

2017–2026

123

Parents

Publications

176

Critical Role for NALP3/CIAS1/Cryopyrin in Innate and Adaptive Immunity through Its Regulation of Caspase-1

Fayyaz S. Sutterwala, Yasunori Ogura, Marian Szczepanik et al. · Immunity · 2006 · 960 citations · Full text

, , +14

Reconstituted NALP1 Inflammasome Reveals Two-Step Mechanism of Caspase-1 Activation

Benjamin Faustin, Lydia Lartigue, Jean‐Marie Bruey et al. · Molecular Cell · 2007 · 698 citations · Full text

, , +13

The Inflammasome-Mediated Caspase-1 Activation Controls Adipocyte Differentiation and Insulin Sensitivity

Rinke Stienstra, Leo A. B. Joosten, Tim B. Koenen et al. · Cell Metabolism · 2010 · 657 citations · Full text

, , +12

The NLRP3 and NLRP1 inflammasomes are activated in Alzheimer’s disease

Marina Saresella, Francesca La Rosa, Federica Piancone et al. · Molecular Neurodegeneration · 2016 · 485 citations · Full text

, , +17

Germline NLRP1 Mutations Cause Skin Inflammatory and Cancer Susceptibility Syndromes via Inflammasome Activation

Franklin L. Zhong, Ons Mamaï, Lorenzo Sborgi et al. · Cell · 2016 · 429 citations · Full text

, , +14

1–5 of 176

Authors

1.2K

  1. WL
    Weizu Li

    Anhui Medical University, China

    13 publications · 463 citations

    12

    h-index

  2. FL
    Franklin L. Zhong

    Nanyang Technological University, Singapore

    12 publications · 1.6K citations

    11

    h-index

  3. KS
    Kim S. Robinson

    Agency for Science, Technology and Research, Singapore

    10 publications · 1.5K citations

    10

    h-index

  4. DA
    Daniel A. Bachovchin

    Memorial Sloan Kettering Cancer Center, United States

    10 publications · 864 citations

    10

    h-index

  5. SL
    Seth L. Masters

    Walter and Eliza Hall Institute of Medical Research, Australia

    8 publications · 1.5K citations

    8

    h-index

1–5 of 1.2K

Institutions

403

  1. Anhui Medical University

    Hefei, China

    16 h-index

    126 publications

    4.7K citations

  2. Agency for Science, Technology and Research

    Singapore, Singapore

    11 h-index

    72 publications

    13.7K citations

  3. Memorial Sloan Kettering Cancer Center

    New York, United States

    10 h-index

    69 publications

    5K citations

  4. Nanyang Technological University

    Singapore, Singapore

    10 h-index

    48 publications

    4.9K citations

  5. Tri-Institutional PhD Program in Chemical Biology

    New York, United States

    10 h-index

    41 publications

    3.1K citations

  6. The University of Melbourne

    Melbourne, Australia

    9 h-index

    44 publications

    7.5K citations

  7. Cornell University

    Ithaca, United States

    9 h-index

    17 publications

    1.2K citations

  8. Institute of Molecular and Cell Biology

    Singapore, Singapore

    8 h-index

    33 publications

    7.6K citations

1–8 of 403

Venues

  1. Journal of Neuroinflammation

    JNI · 6 publications · 442 citations

    6

    h-index

  2. Cell Death and Disease

    6 publications · 728 citations

    6

    h-index

  3. International Immunopharmacology

    6 publications · 229 citations

    6

    h-index

  4. PLoS ONE

    5 publications · 346 citations

    5

    h-index

  5. Proceedings of the National Academy of Sciences

    PNAS · 4 publications · 291 citations

    4

    h-index

1–5