Science · 1984 · 70 citations · 20 references
Molecularly cloned DNA's of human papillomaviruses HPV-5 and HPV-l induced morphological transformation of mouse C127 cells in culture. Single-cell clones of cells transformed by papillomavirus contained multiple persistent episomal copies of the transfected DNA species and were analyzed for growth characteristics indicating malignant potential.
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Matthias Dürst, Lutz Gissmann, Hans Ikenberg et al. · Proceedings of the National Academy of Sciences · 1983 · 2K citations · Full text