The E6 and E7 genes of the human papillomavirus type 16 together are necessary and sufficient for transformation of primary human keratinocytes

Karl Münger, William C. Phelps, Vivien J. Bubb, +2

Journal of Virology

Terminal DifferentiationE7 GenesPrimary Human KeratinocytesHuman Papillomavirus VaccinesImmunology +11

Complex formation of human papillomavirus E7 proteins with the retinoblastoma tumor suppressor gene product.

Karl Münger, Bruce A. Werness, Nicholas J. Dyson, +3

The EMBO Journal

Human Papillomavirus E7PathologyVirologyVirus GeneComplex Formation +5

Structural and transcriptional analysis of human papillomavirus type 16 sequences in cervical carcinoma cell lines

Carl C. Baker, William C. Phelps, Valerie Lindgren, +3

Journal of Virology

Transcriptional AnalysisGeneticsMolecular BiologyPathologyGenomics +16

The human papillomavirus type 16 E7 gene encodes transactivation and transformation functions similar to those of adenovirus E1A

William C. Phelps, Carole Yee, Karl Münger, +1

Cell

Viral ReplicationHuman Papillomavirus VaccinesAdenovirus E1aPathologyVirology +8

Adenovirus E1A, simian virus 40 tumor antigen, and human papillomavirus E7 protein share the capacity to disrupt the interaction between transcription factor E2F and the retinoblastoma gene product.

Srikumar Chellappan, Virginia B. Kraus, Burkhard Kröger, +4

Proceedings of the National Academy of Sciences

Adenovirus E1aPathologyMolecular BiologyTumor BiologyCancer-associated Virus +14

Trans-activation of the human immunodeficiency virus long terminal repeat sequence by DNA viruses.

Howard E. Gendelman, William C. Phelps, Lionel Feigenbaum, +6

Proceedings of the National Academy of Sciences

Bk VirusViral ReplicationMolecular VirologyNatural SciencesHuman Retrovirus +11

Quantitative keratinocyte assay detects two biological activities of human papillomavirus DNA and identifies viral types associated with cervical carcinoma.

Richard Schlegel, William C. Phelps, Yingyue Zhang, +1

The EMBO Journal

Human Papillomavirus DnaPathologyCytopathologyDermatologyCancer-associated Virus +14

Structure-function analysis of the human papillomavirus type 16 E7 oncoprotein

William C. Phelps, Karl Münger, Carole Yee, +2

Journal of Virology

ImmunologyMolecular BiologyPathologyVirus StructureTumor Biology +17

Transcriptional trans-activation by the human papillomavirus type 16 E2 gene product

William C. Phelps, Peter M. Howley

Journal of Virology

Viral ReplicationPathologyMolecular BiologyViral OncologyCancer-associated Virus +17

Analysis of the thymidine kinase genes from acyclovir-resistant mutants of varicella-zoster virus isolated from patients with AIDS

Christine L. Talarico, William C. Phelps, Karen K. Biron

Journal of Virology

Recurrent InfectionsVzv StrainsImmunologyPathologyAntiviral Drug +16