Srikumar Chellappan

The E2F transcription factor is a cellular target for the RB protein

Srikumar Chellappan, Scott W. Hiebert, Maria Mudryj et al. · Cell · 1991 · 1.4K citations

Life Sciences, Genetics, Molecular Biology +13

Adenovirus E1A, simian virus 40 tumor antigen, and human papillomavirus E7 protein share the capacity to disrupt the interaction between transcription factor E2F and the retinoblastoma gene product.

Srikumar Chellappan, Virginia B. Kraus, Burkhard Kröger et al. · Proceedings of the National Academy of Sciences · 1992 · 624 citations · Full text

Medicine, Molecular Biology, Oncology +17

The interaction of RB with E2F coincides with an inhibition of the transcriptional activity of E2F.

Scott W. Hiebert, Srikumar Chellappan, Jordan M. Horowitz et al. · Genes & Development · 1992 · 593 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13

Nicotine induces cell proliferation, invasion and epithelial‐mesenchymal transition in a variety of human cancer cell lines

Piyali Dasgupta, Wasia Rizwani, Smitha Pillai et al. · International Journal of Cancer · 2008 · 376 citations · Full text

Medicine, Oncology, Pharmacology +13

Nicotine inhibits apoptosis induced by chemotherapeutic drugs by up-regulating XIAP and survivin

Piyali Dasgupta, Rebecca Kinkade, Bharat Joshi et al. · Proceedings of the National Academy of Sciences · 2006 · 293 citations · Full text

Medicine, Oncology, Pharmacology +17