Activation of α-secretase by curcumin-aminoacid conjugates

Constitutive and regulated α-secretase cleavage of Alzheimer’s amyloid precursor protein by a disintegrin metalloprotease

Sven Lammich, Elżbieta Kojro, Rolf Postina et al. · Proceedings of the National Academy of Sciences · 1999 · 1.1K citations

Life Sciences, Biochemistry, Molecular Biology +17

Evidence That Tumor Necrosis Factor α Converting Enzyme Is Involved in Regulated α-Secretase Cleavage of the Alzheimer Amyloid Protein Precursor

Joseph D. Buxbaum, Kang-Nian Liu, Yuxia Luo et al. · Journal of Biological Chemistry · 1998 · 916 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Release of Alzheimer Amyloid Precursor Derivatives Stimulated by Activation of Muscarinic Acetylcholine Receptors

Roger M. Nitsch, Barbara E. Slack, Richard J. Wurtman et al. · Science · 1992 · 899 citations

Life Sciences, Neurobiology, Neuroscience +17

Chronic Treatment with the γ-Secretase Inhibitor LY-411,575 Inhibits β-Amyloid Peptide Production and Alters Lymphopoiesis and Intestinal Cell Differentiation

Gwendolyn T. Wong, Denise Manfra, Frederique M. Poulet et al. · Journal of Biological Chemistry · 2004 · 716 citations · Full text

Life Sciences, Immunology, Pharmacology +17

Control of Peripheral Nerve Myelination by the ß-Secretase BACE1

Michael Willem, Alistair N. Garratt, Božidar Novak et al. · Science · 2006 · 686 citations

Medicine, Neurobiology, Neuroscience +17