Concepedia

Secreted Proteases

Secreted Proteases is a type of virulence factor that belongs to the class of extracellular enzymes secreted by pathogens, distinguished by its specific function in cleaving host proteins to facilitate invasion, immune evasion, and nutrient acquisition.

2.1K

Publications

129.9K

Citations

9.2K

Authors

1.9K

Institutions

Publications per year

2017–2026

255

Parents

Publications

2.1K

Identification of a Novel Aspartic Protease (Asp 2) as β-Secretase

Ishrut Hussain, David J. Powell, David Howlett et al. · Molecular and Cellular Neuroscience · 1999 · 1.1K citations

, , +12

Reconstitution of γ-secretase activity

Dieter Edbauer, Edith Winkler, Jörg T. Regula et al. · Nature Cell Biology · 2003 · 875 citations

, , +11

The role of presenilin cofactors in the γ-secretase complex

Nobumasa Takasugi, Taisuke Tomita, Ikuo Hayashi et al. · Nature · 2003 · 867 citations

, , +10

SECRETION OF PLASMINOGEN ACTIVATOR BY STIMULATED MACROPHAGES

Jay C. Unkeless, Saimon Gordon, E. Reich · The Journal of Experimental Medicine · 1974 · 713 citations · Full text

, , +12

Cathepsin C promotes breast cancer lung metastasis by modulating neutrophil infiltration and neutrophil extracellular trap formation

Yansen Xiao, Min Cong, Jiatao Li et al. · Cancer Cell · 2021 · 668 citations

, , +17

1–5 of 2.1K

Authors

9.2K

  1. JP
    Jan Potempa

    Jagiellonian University, Poland

    21 publications · 735 citations

    18

    h-index

  2. MM
    Michel Monod

    University Hospital of Lausanne, Switzerland

    20 publications · 1.3K citations

    18

    h-index

  3. GZ
    Guangming Zhong

    The University of Texas at San Antonio Health Science Center, United States

    17 publications · 1.3K citations

    17

    h-index

  4. EP
    Eleftherios P. Diamandis

    Mount Sinai Hospital, Canada

    14 publications · 1.3K citations

    13

    h-index

  5. MK
    Mogens Kilian

    Aarhus University, Denmark

    14 publications · 882 citations

    13

    h-index

1–5 of 9.2K

Institutions

1.9K

  1. Centre National de la Recherche Scientifique

    Paris, France

    34 h-index

    120 publications

    9.8K citations

  2. University of California, San Francisco

    San Francisco, United States

    30 h-index

    125 publications

    13.5K citations

  3. Inserm

    Paris, France

    29 h-index

    152 publications

    9.7K citations

  4. Washington University in St. Louis

    St Louis, United States

    28 h-index

    94 publications

    10.9K citations

  5. Harvard University

    Cambridge, United States

    22 h-index

    81 publications

    8.5K citations

  6. The University of Texas at San Antonio Health Science Center

    San Antonio, United States

    21 h-index

    72 publications

    5.6K citations

  7. Jagiellonian University

    Krakow, Poland

    20 h-index

    95 publications

    3.4K citations

  8. Institut Pasteur

    Paris, France

    18 h-index

    54 publications

    5.2K citations

1–8 of 1.9K

Venues

  1. Journal of Biological Chemistry

    JBC · 152 publications · 12.4K citations

    64

    h-index

  2. Infection and Immunity

    IAI · 107 publications · 8.3K citations

    58

    h-index

  3. Journal of Bacteriology

    JB · 86 publications · 6.5K citations

    48

    h-index

  4. Proceedings of the National Academy of Sciences

    PNAS · 43 publications · 6.9K citations

    38

    h-index

  5. Molecular Microbiology

    37 publications · 3.9K citations

    33

    h-index

1–5