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Decreased proliferative capacity and increased susceptibility to activation-induced cell death in late-passage human cd4+ tcr2+ cultured T cell clones

T Cell ClonesImmunologyCell DeathAutoimmunityCd4 T Cell ResponsesActivation-induced Cell DeathTolerance InductionCellular Immune ResponseMedicineCell BiologyCell SignalingProliferative CapacityRegulatory T Cell Biology