Endosomal escape and the knockdown efficiency of liposomal-siRNA by the fusogenic peptide shGALA

A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs.

Yasuhiro Matsumura, Hiroshi Maeda · PubMed · 1986 · 6.8K citations

Pathology, Cancer Biology, Cancer Chemotherapy +17

Innate Antiviral Responses by Means of TLR7-Mediated Recognition of Single-Stranded RNA

Sandra S. Diebold, Tsuneyasu Kaisho, Hiroaki Hemmi et al. · Science · 2004 · 3.4K citations

PEGylation significantly affects cellular uptake and intracellular trafficking of non-viral gene delivery particles

Swaroop Mishra, Paul Webster, Mark E. Davis · European Journal of Cell Biology · 2004 · 715 citations

Cell-based Drug Delivery, Nanomedicine, Engineering +10

Tumoritropic and lymphotropic principles of macromolecular drugs.

Hiroshi Maeda, Yasuhiro Matsumura · PubMed · 1989 · 580 citations

Medicinal Chemistry, Mw 16, Drug Targeting +13

Pharmacokinetics of stealth versus conventional liposomes: effect of dose

Theresa M. Allen, Cecilie Cetti Hansen · Biochimica et Biophysica Acta (BBA) - Biomembranes · 1991 · 570 citations

Medicine, Conventional Liposomes, Lipid Movement +2