Genetic variation of Omi/HtrA2 and Parkinson's disease

Score Tests for Association between Traits and Haplotypes when Linkage Phase Is Ambiguous

Daniel J. Schaid, Charles M. Rowland, David E. Tines et al. · The American Journal of Human Genetics · 2002 · 1.8K citations · Full text

Genome-wide Association Study, Linkage Phase, Linkage Disequilibrium +11

Loss of function mutations in the gene encoding Omi/HtrA2 in Parkinson's disease

Karsten M. Strauss, L. Miguel Martins, Hélène Plun‐Favreau et al. · Human Molecular Genetics · 2005 · 563 citations · Full text

Mitophagy, Mitochondrial Dysfunction, Genetics +16

The mitochondrial protease HtrA2 is regulated by Parkinson's disease-associated kinase PINK1

Hélène Plun‐Favreau, Kristina Klupsch, Nicoleta Moisoi et al. · Nature Cell Biology · 2007 · 467 citations

Mitophagy, Biochemistry, Mitochondrial Function +9

Neuroprotective Role of the Reaper-Related Serine Protease HtrA2/Omi Revealed by Targeted Deletion in Mice

L. Miguel Martins, Alastair Morrison, Kristina Klupsch et al. · Molecular and Cellular Biology · 2004 · 396 citations · Full text

Mitophagy, Neuropeptides, Apoptosis +19

Loss of Omi mitochondrial protease activity causes the neuromuscular disorder of mnd2 mutant mice

Julie Miller Jones, Pinaki Datta, Srinivasa M. Srinivasula et al. · Nature · 2003 · 375 citations

Mitochondrial Myopathy, Mitochondrial Function, Medicine +9