Stereospecific synthesis of (−)-carbocyclic 2',3'-Dideoxythymidine, a potential anti-aids agent.

Both 2′,3′-dideoxythymidine and its 2′,3′-unsaturated derivative (2′,3′-dideoxythymidinene) are potent and selective inhibitors of human immunodeficiency virus replication in vitro

Masanori Baba, Rudi Pauwels, Piet Herdewijn et al. · Biochemical and Biophysical Research Communications · 1987 · 344 citations

Life Sciences, Medicinal Chemistry, Molecular Biology +13

Studies in Organophosphorus Chemistry. I. Conversion of Alcohols and Phenols to Halides by Tertiary Phosphine Dihalides

Germany Wiley, Robert Lenard Hershkowitz, Burton Maxwell Rein et al. · Journal of the American Chemical Society · 1964 · 282 citations

Natural Sciences, Chemistry, Analytical Chemistry +5

A novel method for reductive removal of tosyloxy and mesyloxy groups.

Yasuo Fujimoto, Takashi Tatsuno · Tetrahedron Letters · 1976 · 85 citations

Natural Sciences, Biochemistry, Biocatalysis +1

New stereocontrolled synthesis of prostaglandins via prostaglandin A2

E. J. Corey, John Mann · Journal of the American Chemical Society · 1973 · 81 citations

Natural Sciences, Chemistry, Pharmacology +7

Regiospecific prins reaction, a new way to prostanoids

I. Tömösközi, L. Gruber, Go Kovács et al. · Tetrahedron Letters · 1976 · 59 citations

Pharmacy, Chemistry, Medicinal Chemistry +3