Concepedia

Signaling by IL-1β+IFN-γ and ER stress converge on DP5/Hrk activation: a novel mechanism for pancreatic β-cell apoptosis

Esteban N. Gurzov, Fernanda Ortis, Daniel A. Cunha, Guillermo Gosset, Min Li, Alessandra K. Cardozo, Décio L. Eizirik

Cell Death and Differentiation · 2009 · 163 citations · 28 references

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28

Coupling of Stress in the ER to Activation of JNK Protein Kinases by Transmembrane Protein Kinase IRE1

Fumihiko Urano, Xiao-Zhong Wang, Anne Bertolotti et al. · Science · 2000 · 3K citations

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SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase

Brydon L. Bennett, Dennis T. Sasaki, Brion W. Murray et al. · Proceedings of the National Academy of Sciences · 2001 · 2.6K citations · Full text

, , +17

ER Stress Triggers Apoptosis by Activating BH3-Only Protein Bim

Hamsa Puthalakath, Lorraine A. O’Reilly, Priscilla Gunn et al. · Cell · 2007 · 1.4K citations · Full text

, , +14

Hierarchical regulation of mitochondrion-dependent apoptosis by BCL-2 subfamilies

Hyungjin Kim, Mubina Rafiuddin-Shah, Ho-Chou Tu et al. · Nature Cell Biology · 2006 · 858 citations

, , +16

The Burden of Mortality Attributable to Diabetes

Gojka Roglić, Nigel Unwin, Peter H. Bennett et al. · Diabetes Care · 2005 · 820 citations · Full text

, , +17