In silico and in vitro pharmacogenetics: aldehyde oxidase rapidly metabolizes a p38 kinase inhibitor

Casarett and Doull's Toxicology: The Basic Science of Poisons

Annals of Internal Medicine · 1992 · 3.3K citations

Engineering, Nanotoxicology, Chemistry +20

Animal scale-up

Robert L. Dedrick · Journal of Pharmacokinetics and Biopharmaceutics · 1973 · 391 citations

Species similarities and differences in pharmacokinetics.

J H Lin · Drug Metabolism and Disposition · 1995 · 390 citations

Interspecies correlation of plasma concentration history of methotrexate (NSC-740).

Robert L. Dedrick, Kenneth B. Bischoff, Daniel S. Zaharko · PubMed · 1970 · 185 citations

Medicine, Pharmacology, Analytical Chemistry +6

In vitro oxidation of famciclovir and 6-deoxypenciclovir by aldehyde oxidase from human, guinea pig, rabbit, and rat liver.

Mohammad‐Reza Rashidi, John A. Smith, Stephen E. Clarke et al. · PubMed · 1997 · 157 citations

Bioorganic Chemistry, Milk Xanthine Oxidase, Redox Biology +18