Concepedia

Aldehyde Metabolites

Aldehyde Metabolites is a class of reactive metabolite formed during xenobiotic metabolism that is characterized by the presence of an aldehyde functional group, typically resulting from oxidation, hydrolysis, or conjugation reactions and distinguished by its electrophilic nature and potential to cause cellular toxicity.

856

Publications

40.3K

Citations

3.2K

Authors

843

Institutions

Publications per year

2017–2026

97

Parents

Publications

856

Cinnamaldehyde—A potential antidiabetic agent

P. Subash Babu, Seenivasan Prabuseenivasan, Savarimuthu Ignacimuthu · Phytomedicine · 2006 · 480 citations

, , +12

Genotoxic consequences of endogenous aldehydes on mouse haematopoietic stem cell function

Juan I. Garaycoechea, Gerry P. Crossan, Frédéric Langevin et al. · Nature · 2012 · 397 citations

, , +16

Human neutrophils employ the myeloperoxidase-hydrogen peroxide-chloride system to convert hydroxy-amino acids into glycolaldehyde, 2-hydroxypropanal, and acrolein. A mechanism for the generation of highly reactive alpha-hydroxy and alpha,beta-unsaturated aldehydes by phagocytes at sites of inflammation.

M M Anderson, Stanley L. Hazen, Fong‐Fu Hsu et al. · Journal of Clinical Investigation · 1997 · 389 citations · Full text

, , +17

Mammals divert endogenous genotoxic formaldehyde into one-carbon metabolism

Guillermo Burgos-Barragan, Niek J. de Wit, Johannes Meiser et al. · Nature · 2017 · 367 citations · Full text

, , +12

High acetaldehyde levels in saliva after ethanol consumption: methodological aspects and pathogenetic implications

Nils Homann · Carcinogenesis · 1997 · 315 citations · Full text

, , +17

1–5 of 856

Authors

3.2K

  1. NE
    Norman E. Sládek

    University of Minnesota Medical Center, United States

    9 publications · 614 citations

    9

    h-index

  2. AB
    Aruni Bhatnagar

    University of Louisville, United States

    7 publications · 799 citations

    7

    h-index

  3. UD
    Umberto Dianzani

    University of Turin, Italy

    7 publications · 181 citations

    7

    h-index

  4. OT
    Olof Tottmar

    Uppsala University, Sweden

    7 publications · 224 citations

    7

    h-index

  5. SS
    Sanjay Srivastava

    University of Louisville, United States

    6 publications · 820 citations

    6

    h-index

1–5 of 3.2K

Institutions

843

  1. University of Minnesota

    Minneapolis, United States

    11 h-index

    33 publications

    1.5K citations

  2. The University of Texas Medical Branch at Galveston

    Galveston, United States

    10 h-index

    30 publications

    2.8K citations

  3. Uppsala University

    Uppsala, Sweden

    10 h-index

    23 publications

    859 citations

  4. Yamaguchi University

    Yamaguchi, Japan

    9 h-index

    35 publications

    1.5K citations

  5. Rutgers, The State University of New Jersey

    New Brunswick, United States

    9 h-index

    24 publications

    897 citations

  6. University of Turin

    Turin, Italy

    8 h-index

    18 publications

    461 citations

  7. University of Louisville

    Louisville, United States

    8 h-index

    58 publications

    7.6K citations

  8. University of Graz

    Graz, Austria

    7 h-index

    13 publications

    602 citations

1–8 of 843

Venues

  1. PubMed

    Repository · 38 publications · 2K citations

    22

    h-index

  2. Biochemical Pharmacology

    28 publications · 1.2K citations

    21

    h-index

  3. Chemical Research in Toxicology

    24 publications · 1.1K citations

    20

    h-index

  4. Drug Metabolism and Disposition

    22 publications · 1.1K citations

    19

    h-index

  5. Journal of Agricultural and Food Chemistry

    21 publications · 955 citations

    18

    h-index

1–5