Juan I. Garaycoechea

Alcohol and endogenous aldehydes damage chromosomes and mutate stem cells

Juan I. Garaycoechea, Gerry P. Crossan, Frédéric Langevin et al. · Nature · 2018 · 398 citations · Full text

Chromatin, Genome Instability, Dna Damage +9

Genotoxic consequences of endogenous aldehydes on mouse haematopoietic stem cell function

Juan I. Garaycoechea, Gerry P. Crossan, Frédéric Langevin et al. · Nature · 2012 · 388 citations

Developmental Biology, Endogenous Aldehydes, Medicine +11

Endogenous Formaldehyde Is a Hematopoietic Stem Cell Genotoxin and Metabolic Carcinogen

Lucas B. Pontel, Iván V. Rosado, Guillermo Burgos-Barragan et al. · Molecular Cell · 2015 · 385 citations · Full text

Metabolic Carcinogen, Endogenous Formaldehyde, Stem Cell Toxicology +8

Mouse SLX4 Is a Tumor Suppressor that Stimulates the Activity of the Nuclease XPF-ERCC1 in DNA Crosslink Repair

M.R.G. Hodskinson, Jan Šilhán, Gerry P. Crossan et al. · Molecular Cell · 2014 · 136 citations · Full text

Aldehyde-driven transcriptional stress triggers an anorexic DNA damage response

Lee Mulderrig, Juan I. Garaycoechea, Zewen Kelvin Tuong et al. · Nature · 2021 · 133 citations · Full text

Genome Instability, Transcriptional Regulation, Dna Damage +7