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Imidazoles: SAR and development of a potent class of cyclin-dependent kinase inhibitors

Malcolm Anderson, David Andrews, Andy Barker, C. Brassington, J. Breed, Kate F. Byth, Janet D. Culshaw, M. Raymond V. Finlay, Eric F. Fisher, Helen McMiken,

Bioorganic & Medicinal Chemistry Letters · 2008 · 30 citations · 8 references

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8

S and G<sub>2</sub> Phase Roles for Cdk2 Revealed by Inducible Expression of a Dominant-Negative Mutant in Human Cells

Bing Hu, Jayashree Mitra, Sander van den Heuvel et al. · Molecular and Cellular Biology · 2001 · 136 citations · Full text

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Imidazo[1,2-a]pyridines: A potent and selective class of cyclin-Dependent kinase inhibitors identified through structure-Based hybridisation

Malcolm Anderson, John F. Beattie, Gloria A. Breault et al. · Bioorganic & Medicinal Chemistry Letters · 2003 · 114 citations · Full text

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Imidazo[1,2- a ]pyridines. Part 2 : SAR and optimisation of a potent and selective class of cyclin-dependent kinase inhibitors

Kate F. Byth, Janet D. Culshaw, Stephen Green et al. · Bioorganic & Medicinal Chemistry Letters · 2004 · 113 citations · Full text

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Cyclin-Dependent Kinase Inhibition by New C-2 Alkynylated Purine Derivatives and Molecular Structure of a CDK2−Inhibitor Complex

Michel Legraverend, Paul Tunnah, M.E.M. Noble et al. · Journal of Medicinal Chemistry · 2000 · 90 citations · Full text

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Imidazo[1,2- b ]pyridazines: a potent and selective class of cyclin-dependent kinase inhibitors

Kate F. Byth, Nicola J. Cooper, Janet D. Culshaw et al. · Bioorganic & Medicinal Chemistry Letters · 2004 · 73 citations · Full text

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