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Solid-phase synthesis of a small library of 3-phenylthio-3-nicotinyl propionic acid derivatives acting as antagonists of the integrin αVβ3

Paola Vianello, Paolo Cozzi, Arturo Galvani, Maurizio Meroni, Mario Varasi, Daniele Volpi, Tiziano Bandiera

Bioorganic & Medicinal Chemistry Letters · 2004 · 10 citations · 18 references

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References

18

Requirement of Vascular Integrin α <sub>v</sub> β <sub>3</sub> for Angiogenesis

Peter C. Brooks, Richard A.F. Clark, David A. Cheresh · Science · 1994 · 3K citations

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Integrin αvβ3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels

Peter C. Brooks, Anthony M.P. Montgomery, Mauricio Rosenfeld et al. · Cell · 1994 · 2.3K citations

, , +16

Localization of Matrix Metalloproteinase MMP-2 to the Surface of Invasive Cells by Interaction with Integrin αvβ3

Peter C. Brooks, Staffan Strömblad, Luraynne C. Sanders et al. · Cell · 1996 · 1.5K citations · Full text

, , +16

Antiintegrin alpha v beta 3 blocks human breast cancer growth and angiogenesis in human skin.

Peter C. Brooks, Staffan Strömblad, Richard Klemke et al. · Journal of Clinical Investigation · 1995 · 831 citations · Full text

, , +17

Activated integrin αvβ3 cooperates with metalloproteinase MMP-9 in regulating migration of metastatic breast cancer cells

Melanie Rolli, Emilia Fransvea, Ján Pilch et al. · Proceedings of the National Academy of Sciences · 2003 · 330 citations · Full text

, , +17