Daniele Volpi

A Cdc7 kinase inhibitor restricts initiation of DNA replication and has antitumor activity

Alessia Montagnoli, Barbara Valsasina, Valter Croci et al. · Nature Chemical Biology · 2008 · 213 citations · Full text

Cell Regulation, Medicine, Cdc7 Kinase Inhibitor +7

Cdc7 Kinase Inhibitors: Pyrrolopyridinones as Potential Antitumor Agents. 1. Synthesis and Structure–Activity Relationships

Ermes Vanotti, Raffaella Amici, Alberto Bargiotti et al. · Journal of Medicinal Chemistry · 2008 · 94 citations · Full text

Molecular Biology, Structure–activity Relationships, Pharmaceutical Chemistry +16

Identification of 4,5-Dihydro-1<i>H</i>-pyrazolo[4,3-<i>h</i>]quinazoline Derivatives as a New Class of Orally and Selective Polo-Like Kinase 1 Inhibitors

Italo Beria, Dario Ballinari, J. A. Bertrand et al. · Journal of Medicinal Chemistry · 2010 · 80 citations · Full text

Thermodynamics of the high-affinity interaction of TCF4 with β-catenin

Stefan Knapp, Moreno Zamai, Daniele Volpi et al. · Journal of Molecular Biology · 2001 · 67 citations

Chemical Thermodynamics, High-affinity Interaction, Biophysics

First Cdc7 Kinase Inhibitors: Pyrrolopyridinones as Potent and Orally Active Antitumor Agents. 2. Lead Discovery

Maria Menichincheri, Alberto Bargiotti, Jens Berthelsen et al. · Journal of Medicinal Chemistry · 2008 · 66 citations · Full text

Molecular Biology, Pharmacotherapy, Cell Cycle +17