Tregs Promote the Differentiation of Th17 Cells in Silica-Induced Lung Fibrosis in Mice

Abstract

Our study suggested that Tregs could promote Th17 cells differentiation by regulating TGF-β1 and IL-1β in silica induced lung fibrosis of mice, which further the understanding of the progress of silicosis and provide a new insight in the regulatory mechanism of Th17 by Tregs in lung inflammation.