The E Box Motif CAGGTG Enhances Somatic Hypermutation without Enhancing Transcription

Important Advances in Oncology

Vincent T. DeVita, S Hellman, S A Rosenberg · Anti-Cancer Drugs · 1991 · 762 citations

Medicine, Biomedical Sciences, Oncology +3

Transcription-targeted DNA deamination by the AID antibody diversification enzyme

Jayanta Chaudhuri, Ming Tian, Chan Khuong et al. · Nature · 2003 · 734 citations

Life Sciences, Immunology, Molecular Biology +9

Immunoglobulin Isotype Switching Is Inhibited and Somatic Hypermutation Perturbed in UNG-Deficient Mice

Cristina Rada, Gareth T. Williams, Hilde Nilsen et al. · Current Biology · 2002 · 701 citations · Full text

Life Sciences, Immunology, Molecular Biology +16

Activation-induced cytidine deaminase deaminates deoxycytidine on single-stranded DNA but requires the action of RNase

Ronda Bransteitter, Phuong Pham, Matthew D. Scharff et al. · Proceedings of the National Academy of Sciences · 2003 · 676 citations · Full text

Life Sciences, Genetics, Molecular Biology +13

BCL-6 mutations in normal germinal center B cells: Evidence of somatic hypermutation acting outside Ig loci

Laura Pasqualucci, Anna Migliazza, Nicola Fracchiolla et al. · Proceedings of the National Academy of Sciences · 1998 · 540 citations · Full text

Life Sciences, Genetics, Immunology +17