Concepedia

Immunoglobulin Isotype Switching Is Inhibited and Somatic Hypermutation Perturbed in UNG-Deficient Mice

Cristina Rada, Gareth T. Williams, Hilde Nilsen, Deborah E. Barnes, Tomas Lindahl, Michael S. Neuberger

Current Biology · 2002 · 701 citations · 34 references

DOIFull text

Open access

Concepts

References

34

Class Switch Recombination and Hypermutation Require Activation-Induced Cytidine Deaminase (AID), a Potential RNA Editing Enzyme

Masamichi Muramatsu, Kazuo Kinoshita, Sidonia Fagarasan et al. · Cell · 2000 · 3.4K citations

, , +14

Activation-Induced Cytidine Deaminase (AID) Deficiency Causes the Autosomal Recessive Form of the Hyper-IgM Syndrome (HIGM2)

Patrick Revy, Taro Muto, Yves Lévy et al. · Cell · 2000 · 1.6K citations · Full text

, , +13

The V(D)J recombination activating gene, RAG-1

David G. Schatz, Marjorie A. Oettinger, David Baltimore · Cell · 1989 · 1.2K citations · Full text

, , +11

Specific Expression of Activation-induced Cytidine Deaminase (AID), a Novel Member of the RNA-editing Deaminase Family in Germinal Center B Cells

Masamichi Muramatsu, V.S. Sankaranand, Shrikant Anant et al. · Journal of Biological Chemistry · 1999 · 1.2K citations · Full text

, , +15

AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification

Svend K. Petersen‐Mahrt, Reuben S. Harris, Michael S. Neuberger · Nature · 2002 · 888 citations

, , +12