Toward minimalistic modeling of oral drug absorption

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

Christopher A. Lipinski, Franco Lombardo, Beryl W. Dominy et al. · Advanced Drug Delivery Reviews · 1997 · 11.2K citations

Pharmacy, Pharmacokinetics, Pharmacology +16

The Collinearity Problem in Linear Regression. The Partial Least Squares (PLS) Approach to Generalized Inverses

Svante Wold, Axel Ruhe, Herman Wold et al. · SIAM Journal on Scientific and Statistical Computing · 1984 · 2.5K citations

Pharmacy, Biochemistry, Biomolecular Modeling +12

Cross-Validatory Estimation of the Number of Components in Factor and Principal Components Models

Svante Wold · Technometrics · 1978 · 2.5K citations

Business, Biostatistics, Mass Spectrometric Analysis +10

PLS regression methods

Agnar Höskuldsson · Journal of Chemometrics · 1988 · 1.9K citations

Business, Computer Science, Data Science +15

Correlation between oral drug absorption in humans and apparent drug permeability coefficients in human intestinal epithelial (Caco-2) cells

Per Artursson, Johan Karlsson · Biochemical and Biophysical Research Communications · 1991 · 1.9K citations

Pharmacy, Pharmacokinetics, Pharmacology +16