Concepedia

Opposing effects of Ets and Id proteins on p16INK4a expression during cellular senescence

Naoko Ohtani, Zoë Zebedee, Thomas J. G. Huot, Julie A. Stinson, Masataka Sugimoto, Yasuhiro Ohashi, Andrew D Sharrocks, Gordon Peters, Eiji Hara

Nature · 2001 · 641 citations · 22 references

DOI

Concepts

References

22

The serial cultivation of human diploid cell strains

Leonard Hayflick, Paul S. Moorhead · Experimental Cell Research · 1961 · 8.4K citations

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A biomarker that identifies senescent human cells in culture and in aging skin in vivo.

Goberdhan P. Dimri, X Lee, George Basile et al. · Proceedings of the National Academy of Sciences · 1995 · 7.4K citations · Full text

, , +15

Telomeres shorten during ageing of human fibroblasts

Calvin B. Harley, A. B. Futcher, Carol W. Greider · Nature · 1990 · 5.7K citations

, , +11

Oncogenic ras Provokes Premature Cell Senescence Associated with Accumulation of p53 and p16INK4a

Manuel Serrano, Athena W. Lin, Mila E. McCurrach et al. · Cell · 1997 · 5.1K citations · Full text

, , +10

A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4

Manuel Serrano, Gregory J. Hannon, David Beach · Nature · 1993 · 3.7K citations

, , +17