Eiji Hara

Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome

Shin Yoshimoto, Tze Mun Loo, Koji Atarashi et al. · Nature · 2013 · 2.1K citations

Obesity, Systems Biology, Dysbiosis +12

An Essential Role for Senescent Cells in Optimal Wound Healing through Secretion of PDGF-AA

Marco Demaria, Naoko Ohtani, Sameh A. Youssef et al. · Developmental Cell · 2014 · 1.9K citations · Full text

Inflammation, Essential Role, Optimal Wound Healing +10

Exosomes maintain cellular homeostasis by excreting harmful DNA from cells

Akiko Takahashi, Ryo Okada, Koji Nagao et al. · Nature Communications · 2017 · 726 citations · Full text

Regulation of p16<i>^CDKN2</i> Expression and Its Implications for Cell Immortalization and Senescence

Eiji Hara, Rosalind Smith, David Parry et al. · Molecular and Cellular Biology · 1996 · 719 citations · Full text

Transcriptional Regulation, Signal Transduction, Signaling Pathway +13

Opposing effects of Ets and Id proteins on p16INK4a expression during cellular senescence

Naoko Ohtani, Zoë Zebedee, Thomas J. G. Huot et al. · Nature · 2001 · 638 citations

Developmental Biology, Signaling Pathway, Cellular Senescence +6