Concepedia

Synthesis of metabolically blocked paclitaxel analogues

Mark D. Wittman, Thomas J. Altstadt, Craig R. Fairchild, Stephen Hansel, Kathy Johnston, John F. Kadow, Byron H. Long, William C. Rose, Dolatrai M. Vyas, Mu-Jen Wu,

Bioorganic & Medicinal Chemistry Letters · 2001 · 14 citations · 8 references

DOI

Concepts

References

8

Promotion of microtubule assembly in vitro by taxol

Peter B. Schiff, Jane Fant, Susan Band Horwitz · Nature · 1979 · 3.6K citations

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Vicinal diol cyclic sulfates. Like epoxides only more reactive

Yun Gao, K. Barry Sharpless · Journal of the American Chemical Society · 1988 · 542 citations

, , +5

Taxol metabolism and disposition in cancer patients.

Thomas Walle, U. Kristina Walle, Gondi Kumar et al. · Drug Metabolism and Disposition · 1995 · 137 citations

, , +17

Tissue distribution, metabolism and excretion of paclitaxel in mice

Alex Sparreboom, Olaf van Tellingen, Willem J. Nooijen et al. · Anti-Cancer Drugs · 1996 · 128 citations

, , +8

Isolation, Structural Determination, and Biological Activity of 6.alpha.-Hydroxytaxol, the Principal Human Metabolite of Taxol

James W. Harris, Aspandiar G. Katki, Lawrence W. Anderson et al. · Journal of Medicinal Chemistry · 1994 · 99 citations

, , +14