Willem J. Nooijen

Limited oral bioavailability and active epithelial excretion of paclitaxel (Taxol) caused by P-glycoprotein in the intestine

Alex Sparreboom, Judith van Asperen, Ulrich Mayer et al. · Proceedings of the National Academy of Sciences · 1997 · 880 citations

Pharmacy, Pharmacokinetics, Pharmacology +15

Randomised trial of high-dose chemotherapy and haemopoietic progenitor-cell support in operable breast cancer with extensive axillary lymph-node involvement

Sjoerd Rodenhuis, Dick J. Richel, Elsken van der Wall et al. · The Lancet · 1998 · 243 citations

Medicine, Oncology, Breast Oncology +16

Tissue distribution, metabolism and excretion of paclitaxel in mice

Alex Sparreboom, Olaf van Tellingen, Willem J. Nooijen et al. · Anti-Cancer Drugs · 1996 · 128 citations

Pharmacy, Pharmacokinetics, Pharmacology +8

Immunogenicity, Including Vitiligo, and Feasibility of Vaccination With Autologous<i>GM-CSF</i>–Transduced Tumor Cells in Metastatic Melanoma Patients

Rosalie M. Luiten, Esther W. M. Kueter, Wolter J. Mooi et al. · Journal of Clinical Oncology · 2005 · 106 citations · Full text

Medicine, Immunology, Oncology +17

Isolation, purification, and biological activity of mono- and dihydroxylated paclitaxel metabolites from human feces

Alexander Sparreboom, Manon Huizing, Jan J. B. Boesen et al. · Cancer Chemotherapy and Pharmacology · 1995 · 66 citations

Life Sciences, Biochemistry, Pharmacology +14