Judith van Asperen

Limited oral bioavailability and active epithelial excretion of paclitaxel (Taxol) caused by P-glycoprotein in the intestine

Alex Sparreboom, Judith van Asperen, Ulrich Mayer et al. · Proceedings of the National Academy of Sciences · 1997 · 877 citations · Full text

Active Epithelial Excretion, Gastrointestinal Pharmacology, Immunology +16

Enhanced oral bioavailability of paclitaxel in mice treated with the P-glycoprotein blocker SDZ PSC 833

Judith van Asperen, Olaf van Tellingen, Alex Sparreboom et al. · British Journal of Cancer · 1997 · 202 citations · Full text

Molecular Pharmacology, Medicine, Experimental Pharmacology +6

Altered Pharmacokinetics of Vinblastine in Mdr1a P-glycoprotein-Deficient Mice

Judith van Asperen, Alfred H. Schinkel, Jos H. Beijnen et al. · JNCI Journal of the National Cancer Institute · 1996 · 176 citations

Increased accumulation of doxorubicin and doxorubicinol in cardiac tissue of mice lacking mdr1a P-glycoprotein

Judith van Asperen, Olaf van Tellingen, Frank Tijssen et al. · British Journal of Cancer · 1998 · 148 citations · Full text

Cardiac Muscle, Cardiovascular Pharmacology, Pharmacotherapy +17

Enhanced oral absorption and decreased elimination of paclitaxel in mice cotreated with cyclosporin A.

Judith van Asperen, Olaf van Tellingen, Martin A. van der Valk et al. · PubMed · 1998 · 140 citations

Oral Bioavailability, Immunology, Cyclosporin A +20