Kathy Johnston

Discovery of <i>N</i>-(2-Chloro-6-methyl- phenyl)-2-(6-(4-(2-hydroxyethyl)- piperazin-1-yl)-2-methylpyrimidin-4- ylamino)thiazole-5-carboxamide (BMS-354825), a Dual Src/Abl Kinase Inhibitor with Potent Antitumor Activity in Preclinical Assays

Louis J. Lombardo, Francis Y. Lee, Ping Chen et al. · Journal of Medicinal Chemistry · 2004 · 1.3K citations · Full text

Medicine, Oncology, Pharmacology +13

Sensitivity of Small Cell Lung Cancer to BET Inhibition Is Mediated by Regulation of <i>ASCL1</i> Gene Expression

Ryan Lenhart, Stefan Kirov, Heshani Desilva et al. · Molecular Cancer Therapeutics · 2015 · 96 citations

Medicine, Molecular Biology, Oncology +17

Preclinical efficacy spectrum and pharmacokinetics of ixabepilone

Francis Y. F. Lee, Richard Smykla, Kathy Johnston et al. · Cancer Chemotherapy and Pharmacology · 2008 · 96 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +15

Synthesis and Biological Evaluation of 2-Acyl Analogues of Paclitaxel (Taxol)

David G. I. Kingston, Ashok Chaudhary, Mahendra D. Chordia et al. · Journal of Medicinal Chemistry · 1998 · 65 citations

Medicine, Medicinal Chemistry, Pharmacology +12

Synthesis and Antitumor Activity of Novel C-7 Paclitaxel Ethers:  Discovery of BMS-184476

Thomas J. Altstadt, Craig R. Fairchild, Jerzy Golik et al. · Journal of Medicinal Chemistry · 2001 · 58 citations

Pharmacy, Medicinal Chemistry, Pharmacology +15