Francis Y. F. Lee - Concepedia

Author

Francis Y. F. Lee

Bristol-Myers Squibb (United States)

Also Known As

F Y Lee, Francis Y. F. Lee, Francis Y.F. Lee, Lee, F.Y.F.

Publications

3.3K

Citations

H-Index

Concepts

All Affiliations

Bristol-Myers Squibb (United States)Bristol-Myers Squibb (Germany)Helsinki University Hospital

About

Francis Y. F. Lee is an author at Bristol-Myers Squibb (United States) specializing in pharmacology, medicine, and drug discovery.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	12	12	1.4K
2	Natural Sciences	3	3	266
3	Biochemistry	3	3	266
4	Engineering	2	2	213
5	Health Sciences	1	1	251

Francis Y. F. Lee

Publications

3.1K

Citations

H-Index

Page 1

	Year	Citations
The Structure of Dasatinib (BMS-354825) Bound to Activated ABL Kinase Domain Elucidates Its Inhibitory Activity against Imatinib-Resistant ABL Mutants John S. Tokarski, John A. Newitt, Chieh Ying J. Chang, Cancer Research	2006	677
BMS-247550: a novel epothilone analog with a mode of action similar to paclitaxel but possessing superior antitumor efficacy. Francis Y. F. Lee, R. M. Borzilleri, Craig R. Fairchild, PubMed PharmacotherapyTumor BiologySuperior Antitumor EfficacyTubulin MutationNovel Epothilone Derivative	2001	455
Dasatinib crosses the blood-brain barrier and is an efficient therapy for central nervous system Philadelphia chromosome–positive leukemia Kimmo Porkka, Perttu Koskenvesa, Tuija Lundán, Blood	2008	437
<i>N</i>-(Cycloalkylamino)acyl-2-aminothiazole Inhibitors of Cyclin-Dependent Kinase 2. <i>N</i>-[5-[[[5-(1,1-Dimethylethyl)-2-oxazolyl]methyl]thio]-2-thiazolyl]-4- piperidinecarboxamide (BMS-387032), a Highly Efficacious and Selective Antitumor Agent Raj N. Misra, Hai‐Yun Xiao, Kyoung S. Kim, Journal of Medicinal Chemistry Chemoprevention StrategyImmunologyPharmacotherapyCdk2/cyce IcPharmaceutical Chemistry	2004	251
Metabolism and Disposition of Dasatinib after Oral Administration to Humans Lisa J. Christopher, Donghui Cui, Chi‐Yuan Wu, Drug Metabolism and Disposition	2008	194
A Novel Application of a Pd(0)-Catalyzed Nucleophilic Substitution Reaction to the Regio- and Stereoselective Synthesis of Lactam Analogues of the Epothilone Natural Products R. M. Borzilleri, Xiaoping Zheng, Robert J. Schmidt, Journal of the American Chemical Society Several LactamEngineeringOrganic ChemistryChemistryPharmaceutical Chemistry	2000	141
Discovery of (<i>R</i>)-7-Cyano-2,3,4,5-tetrahydro-1-(1<i>H</i>-imidazol-4-ylmethyl)-3- (phenylmethyl)-4-(2-thienylsulfonyl)-1<i>H</i>-1,4-benzodiazepine (BMS-214662), a Farnesyltransferase Inhibitor with Potent Preclinical Antitumor Activity John T. Hunt, Charles Z. Ding, Roberta S. Batorsky, Journal of Medicinal Chemistry Medicinal Chemistry-1,4-Benzodiazepine FarnesyltransferaseBiochemistryChemoprevention StrategyMedicine	2000	134
Targeting DDR2 enhances tumor response to anti–PD-1 immunotherapy Megan M. Tu, Francis Y. F. Lee, Robert T. Jones, Science Advances	2019	124
Preclinical antitumor activity of BMS-214662, a highly apoptotic and novel farnesyltransferase inhibitor. William C. Rose, Francis Y. F. Lee, Craig R. Fairchild, PubMed Medicinal ChemistryOncogenic AgentMedicineLewis Lung CarcinomaCancer Cell Biology	2001	108
Preclinical efficacy spectrum and pharmacokinetics of ixabepilone Francis Y. F. Lee, Richard Smykla, Kathy Johnston, Cancer Chemotherapy and Pharmacology	2008	95

Page 1