Francis Y. F. Lee

The Structure of Dasatinib (BMS-354825) Bound to Activated ABL Kinase Domain Elucidates Its Inhibitory Activity against Imatinib-Resistant ABL Mutants

John S. Tokarski, John A. Newitt, Chieh Ying J. Chang et al. · Cancer Research · 2006 · 677 citations · Full text

BMS-247550: a novel epothilone analog with a mode of action similar to paclitaxel but possessing superior antitumor efficacy.

Francis Y. F. Lee, R. M. Borzilleri, Craig R. Fairchild et al. · PubMed · 2001 · 455 citations

Pharmacotherapy, Tumor Biology, Superior Antitumor Efficacy +17

Dasatinib crosses the blood-brain barrier and is an efficient therapy for central nervous system Philadelphia chromosome–positive leukemia

Kimmo Porkka, Perttu Koskenvesa, Tuija Lundán et al. · Blood · 2008 · 437 citations · Full text

<i>N</i>-(Cycloalkylamino)acyl-2-aminothiazole Inhibitors of Cyclin-Dependent Kinase 2. <i>N</i>-[5-[[[5-(1,1-Dimethylethyl)-2-oxazolyl]methyl]thio]-2-thiazolyl]-4- piperidinecarboxamide (BMS-387032), a Highly Efficacious and Selective Antitumor Agent

Raj N. Misra, Hai‐Yun Xiao, Kyoung S. Kim et al. · Journal of Medicinal Chemistry · 2004 · 251 citations · Full text

Chemoprevention Strategy, Immunology, Pharmacotherapy +19

Metabolism and Disposition of Dasatinib after Oral Administration to Humans

Lisa J. Christopher, Donghui Cui, Chi‐Yuan Wu et al. · Drug Metabolism and Disposition · 2008 · 194 citations