R. M. Borzilleri

Discovery of <i>N</i>-(2-Chloro-6-methyl- phenyl)-2-(6-(4-(2-hydroxyethyl)- piperazin-1-yl)-2-methylpyrimidin-4- ylamino)thiazole-5-carboxamide (BMS-354825), a Dual Src/Abl Kinase Inhibitor with Potent Antitumor Activity in Preclinical Assays

Louis J. Lombardo, Francis Y. Lee, Ping Chen et al. · Journal of Medicinal Chemistry · 2004 · 1.3K citations · Full text

Medicine, Oncology, Pharmacology +13

BMS-247550: a novel epothilone analog with a mode of action similar to paclitaxel but possessing superior antitumor efficacy.

Francis Y. F. Lee, R. M. Borzilleri, Craig R. Fairchild et al. · PubMed · 2001 · 455 citations

Medicine, Oncology, Pharmacology +13

Discovery of <i>N</i>-(4-(2-Amino-3-chloropyridin-4-yloxy)-3-fluorophenyl)-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide (BMS-777607), a Selective and Orally Efficacious Inhibitor of the Met Kinase Superfamily

Gretchen M. Schroeder, Yongmi An, Zhen‐Wei Cai et al. · Journal of Medicinal Chemistry · 2009 · 277 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13

Immune-modulating enzyme indoleamine 2,3-dioxygenase is effectively inhibited by targeting its apo-form

Micah T. Nelp, Patrick A. Kates, John T. Hunt et al. · Proceedings of the National Academy of Sciences · 2018 · 208 citations · Full text

Life Sciences, Immunology, Molecular Biology +14

Decarboxylative Peptide Macrocyclization through Photoredox Catalysis

Stefan J. McCarver, Jennifer X. Qiao, Joseph Carpenter et al. · Angewandte Chemie International Edition · 2016 · 150 citations

Pharmacy, Medicinal Chemistry, Pharmacology +13