John T. Hunt

Discovery of <i>N</i>-(2-Chloro-6-methyl- phenyl)-2-(6-(4-(2-hydroxyethyl)- piperazin-1-yl)-2-methylpyrimidin-4- ylamino)thiazole-5-carboxamide (BMS-354825), a Dual Src/Abl Kinase Inhibitor with Potent Antitumor Activity in Preclinical Assays

Louis J. Lombardo, Francis Y. Lee, Ping Chen et al. · Journal of Medicinal Chemistry · 2004 · 1.3K citations · Full text

Drug Target, Preclinical Assays, Pharmacotherapy +19

Lawson Criterion for Ignition Exceeded in an Inertial Fusion Experiment

H. Abu-Shawareb, Robert L. Acree, P. A. Adams et al. · Physical Review Letters · 2022 · 459 citations · Full text

Engineering, Physics, Aerospace Engineering +11

Achievement of Target Gain Larger than Unity in an Inertial Fusion Experiment

H. Abu-Shawareb, Robert L. Acree, P. A. Adams et al. · Physical Review Letters · 2024 · 329 citations · Full text

Discovery of <i>N</i>-(4-(2-Amino-3-chloropyridin-4-yloxy)-3-fluorophenyl)-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide (BMS-777607), a Selective and Orally Efficacious Inhibitor of the Met Kinase Superfamily

Gretchen M. Schroeder, Yongmi An, Zhen‐Wei Cai et al. · Journal of Medicinal Chemistry · 2009 · 276 citations · Full text

Orally Efficacious Inhibitor, Drug Target, Pharmacotherapy +21

Venous smooth muscle contains vasoconstrictor ETB-like receptors

Suzanne Moreland, Diane M. McMullen, Carol L. Delaney et al. · Biochemical and Biophysical Research Communications · 1992 · 256 citations

Venous Disease, Molecular Physiology, Etb-like Receptors +6