Dolatrai M. Vyas

BMS-754807, a small molecule inhibitor of insulin-like growth factor-1R/IR

Joan M. Carboni, Mark D. Wittman, Zheng Yang et al. · Molecular Cancer Therapeutics · 2009 · 278 citations · Full text

Small Molecule Inhibitor, Cancer Biology, Insulin Signaling +16

Stephacidin A and B:  Two Structurally Novel, Selective Inhibitors of the Testosterone-Dependent Prostate LNCaP Cells

Jingfang Qian‐Cutrone, Stella Huang, Yue‐Zhong Shu et al. · Journal of the American Chemical Society · 2002 · 221 citations

Secondary Metabolite, Selective Inhibitors, Pharmacotherapy +19

Discovery of a 1<i>H</i>-Benzoimidazol-2-yl)-1<i>H</i>-pyridin-2-one (BMS-536924) Inhibitor of Insulin-like Growth Factor I Receptor Kinase with in Vivo Antitumor Activity

Mark D. Wittman, Joan M. Carboni, Ricardo M. Attar et al. · Journal of Medicinal Chemistry · 2005 · 134 citations · Full text

Pharmacotherapy, Insulin Receptor, Insulin Signaling +21

2-Aryl-2,2-difluoroacetamide FKBP12 Ligands:  Synthesis and X-ray Structural Studies

Gene M. Dubowchik, Vivekananda M. Vrudhula, Bireshwar Dasgupta et al. · Organic Letters · 2001 · 103 citations

Chemical Biology, X-ray Structural Studies, Halogenation +15

Discovery of a 2,4-Disubstituted Pyrrolo[1,2-<i>f</i>][1,2,4]triazine Inhibitor (BMS-754807) of Insulin-like Growth Factor Receptor (IGF-1R) Kinase in Clinical Development

Mark D. Wittman, Joan M. Carboni, Yang Zheng et al. · Journal of Medicinal Chemistry · 2009 · 94 citations · Full text