Concepedia

The Ubiquitin Ligase TRIM56 Regulates Innate Immune Responses to Intracellular Double-Stranded DNA

Tetsuo Tsuchida, Jian Zou, Tatsuya Saitoh, Himanshu Kumar, Takayuki Abe, Yoshiharu Matsuura, Taro Kawai, Shizuo Akira

Immunity · 2010 · 491 citations · 30 references

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30

STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling

Hiroki Ishikawa, Glen N. Barber · Nature · 2008 · 3.5K citations · Full text

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STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity

Hiroki Ishikawa, Zhe Ma, Glen N. Barber · Nature · 2009 · 2.7K citations · Full text

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AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC

Veit Hornung, Andrea Ablasser, Marie Charrel-Dennis et al. · Nature · 2009 · 2.6K citations · Full text

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IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction

Taro Kawai, Ken Takahashi, Shintaro Sato et al. · Nature Immunology · 2005 · 2.5K citations

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AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA

Teresa Fernandes‐Alnemri, Je‐Wook Yu, Pinaki Datta et al. · Nature · 2009 · 1.8K citations · Full text

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