Concepedia

Impaired Activation of the Nrf2-ARE Signaling Pathway Undermines H2O2-Induced Oxidative Stress Response: A Possible Mechanism for Melanocyte Degeneration in Vitiligo

Zhe Jian, Kai Li, Pu Song, Guannan Zhu, Longfei Zhu, Tingting Cui, Bangmin Liu, Lingzhen Tang, Xiaowen Wang, Gang Wang,

Journal of Investigative Dermatology · 2014 · 195 citations · 43 references

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43

Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants

Albena T. Dinkova‐Kostova, W. David Holtzclaw, Robert N. Cole et al. · Proceedings of the National Academy of Sciences · 2002 · 1.9K citations · Full text

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Nrf2-regulated glutathione recycling independent of biosynthesis is critical for cell survival during oxidative stress

Christopher J. Harvey, Rajesh K. Thimmulappa, Anju Singh et al. · Free Radical Biology and Medicine · 2008 · 528 citations

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Action of Nrf2 and Keap1 in ARE-mediated NQO1 expression by quercetin

Shunsuke Tanigawa · Free Radical Biology and Medicine · 2007 · 483 citations

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Contribution of impaired Nrf2-Keap1 pathway to oxidative stress and inflammation in chronic renal failure

Hyun Ju Kim, Nosratola D. Vaziri · American Journal of Physiology-Renal Physiology · 2009 · 469 citations

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Role of Nrf2 signaling in regulation of antioxidants and phase 2 enzymes in cardiac fibroblasts: Protection against reactive oxygen and nitrogen species‐induced cell injury

Hong Zhu, Ken Itoh, Masayuki Yamamoto et al. · FEBS Letters · 2005 · 389 citations

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