Impaired Activation of the Nrf2-ARE Signaling Pathway Undermines H2O2-Induced Oxidative Stress Response: A Possible Mechanism for Melanocyte Degeneration in Vitiligo

Zhe Jian, Kai Li, Pu Song, +9

Journal of Investigative Dermatology

Reductive StressSignal TransductionBiochemistryRedox RegulatorLipid Peroxidation +11

Nrf2 Promotes Keratinocyte Proliferation in Psoriasis through Up-Regulation of Keratin 6, Keratin 16, and Keratin 17

Luting Yang, Xueli Fan, Tingting Cui, +2

Journal of Investigative Dermatology

InflammationSkin DevelopmentKeratin 16Cutaneous BiologyImmunology +6

SIRT3-Dependent Mitochondrial Dynamics Remodeling Contributes to Oxidative Stress-Induced Melanocyte Degeneration in Vitiligo

Xiuli Yi, Weinan Guo, Qiong Shi, +17

Theranostics

Dysregulated autophagy increased melanocyte sensitivity to H2O2-induced oxidative stress in vitiligo

Yuanmin He, Shuli Li, Weigang Zhang, +5

Scientific Reports

Oxidative Stress–Induced HMGB1 Release from Melanocytes: A Paracrine Mechanism Underlying the Cutaneous Inflammation in Vitiligo

Tingting Cui, Weigang Zhang, Shuli Li, +13

Journal of Investigative Dermatology

InflammationParacrine MechanismRedox SignalingCutaneous BiologyImmunology +7

Oxidative stress-induced IL-15 trans-presentation in keratinocytes contributes to CD8+ T cells activation via JAK-STAT pathway in vitiligo

Xuguang Chen, Weinan Guo, Yuqian Chang, +12

Free Radical Biology and Medicine

InflammationCytokineAutoimmune DiseaseT-regulatory CellJak-stat Pathway +11

Baicalein protects human vitiligo melanocytes from oxidative stress through activation of NF-E2-related factor2 (Nrf2) signaling pathway

Jingjing Ma, Shuli Li, Longfei Zhu, +8

Free Radical Biology and Medicine

InflammationReductive StressRedox SignalingRedox RegulatorCell Signaling +9

Simvastatin Protects Human Melanocytes from H2O2-Induced Oxidative Stress by Activating Nrf2

Yuqian Chang, Shuli Li, Weinan Guo, +15

Journal of Investigative Dermatology

InflammationSignal TransductionMedicineActivating Nrf2Physiology +11

Combined treatment with sorafenib and silibinin synergistically targets both HCC cells and cancer stem cells by enhanced inhibition of the phosphorylation of STAT3/ERK/AKT

Jie Mao, Hongbao Yang, Tingting Cui, +7

European Journal of Pharmacology

Health SciencesMedicineReceptor Tyrosine KinasePharmacologyAnti-cancer Agent +6

Oxeiptosis: a novel pathway of melanocytes death in response to oxidative stress in vitiligo

Pan Kang, Jianru Chen, Weigang Zhang, +11

Cell Death Discovery