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Design and synthesis of novel series of pyrrole based chemotypes and their evaluation as selective aldose reductase inhibitors. A case of bioisosterism between a carboxylic acid moiety and that of a tetrazole

Medicinal ChemistryBioorganic ChemistryNovel SeriesBiochemistryNatural SciencesMedicineOrganic ChemistryStereoselective SynthesisCarboxylic Acid MoietyPharmacologyPharmaceutical ChemistrySynthetic ChemistryDrug DiscoveryNatural Product Synthesis