Vassilis J. Demopoulos

Isomeric Benzoylpyrroleacetic Acids: Some Structural Aspects for Aldose Reductase Inhibitory and Anti-Inflammatory Activities

Vassilis J. Demopoulos, Eleni A. Rekka · Journal of Pharmaceutical Sciences · 1995 · 86 citations

Medicinal Chemistry, Bioorganic Chemistry, Aldehyde Dehydrogenase +11

Design and synthesis of novel series of pyrrole based chemotypes and their evaluation as selective aldose reductase inhibitors. A case of bioisosterism between a carboxylic acid moiety and that of a tetrazole

Kyriaki Pegklidou, Catherine Koukoulitsa, Ioannis Nicolaou et al. · Bioorganic & Medicinal Chemistry · 2010 · 70 citations · Full text

Medicinal Chemistry, Bioorganic Chemistry, Novel Series +11

Carboxymethylated pyridoindole antioxidants as aldose reductase inhibitors: Synthesis, activity, partitioning, and molecular modeling

Milan Štefek, Vladimír Šnirc, Paul-Omer Djoubissie et al. · Bioorganic & Medicinal Chemistry · 2008 · 66 citations · Full text

Medicinal Chemistry, Aldo-keto Reductase, Biochemistry +11

Substituted Pyrrol-1-ylacetic Acids That Combine Aldose Reductase Enzyme Inhibitory Activity and Ability To Prevent the Nonenzymatic Irreversible Modification of Proteins from Monosaccharides

Ioannis Nicolaou, Vassilis J. Demopoulos · Journal of Medicinal Chemistry · 2002 · 64 citations · Full text

A Diverse Series of Substituted Benzenesulfonamides as Aldose Reductase Inhibitors with Antioxidant Activity: Design, Synthesis, and in Vitro Activity

Polyxeni Alexiou, Vassilis J. Demopoulos · Journal of Medicinal Chemistry · 2010 · 62 citations · Full text