Mechanisms of transthyretin cardiomyocyte toxicity inhibition by resveratrol analogs

Investigation of the Alamar Blue (resazurin) fluorescent dye for the assessment of mammalian cell cytotoxicity

John O’Brien, Ian D. Wilson, Terry C. Orton et al. · European Journal of Biochemistry · 2000 · 3.4K citations · Full text

Dentistry, Biochemistry, Cell Biology +14

Variant-Sequence Transthyretin (Isoleucine 122) in Late-Onset Cardiac Amyloidosis in Black Americans

Daniel R. Jacobson, Raymond D. Pastore, Robert Yaghoubian et al. · New England Journal of Medicine · 1997 · 553 citations · Full text

Life Sciences, Cardiology, Genetics +11

The Biological and Chemical Basis for Tissue-Selective Amyloid Disease

Yoshiki Sekijima, R. Luke Wiseman, Jeanne Matteson et al. · Cell · 2005 · 494 citations · Full text

Life Sciences, Biochemistry, Neuroscience +14

Tissue damage in the amyloidoses: Transthyretin monomers and nonnative oligomers are the major cytotoxic species in tissue culture

Natàlia Reixach, Songpon Deechongkit, Xin Jiang et al. · Proceedings of the National Academy of Sciences · 2004 · 384 citations · Full text

Life Sciences, Molecular Biology, Neuroscience +17

Rational design of potent human transthyretin amyloid disease inhibitors.

James C. Sacchettini, Thomas Klabunde, H. Michael Petrassi et al. · Nature Structural Biology · 2000 · 370 citations

Pharmacy, Medicinal Chemistry, Pharmacology +12