Xin Jiang

Tissue damage in the amyloidoses: Transthyretin monomers and nonnative oligomers are the major cytotoxic species in tissue culture

Natàlia Reixach, Songpon Deechongkit, Xin Jiang et al. · Proceedings of the National Academy of Sciences · 2004 · 384 citations · Full text

Life Sciences, Molecular Biology, Neuroscience +17

Sequence-dependent denaturation energetics: A major determinant in amyloid disease diversity

Per Hammarström, Xin Jiang, Amy R. Hurshman et al. · Proceedings of the National Academy of Sciences · 2002 · 355 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

An Engineered Transthyretin Monomer that Is Nonamyloidogenic, Unless It Is Partially Denatured

Xin Jiang, Craig S. Smith, H. Michael Petrassi et al. · Biochemistry · 2001 · 238 citations

Life Sciences, Biochemistry, Molecular Biology +17

The V122I cardiomyopathy variant of transthyretin increases the velocity of rate-limiting tetramer dissociation, resulting in accelerated amyloidosis

Xin Jiang, Joel N. Buxbaum, Jeffery W. Kelly · Proceedings of the National Academy of Sciences · 2001 · 167 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Potent and Selective Structure-Based Dibenzofuran Inhibitors of Transthyretin Amyloidogenesis:  Kinetic Stabilization of the Native State

H. Michael Petrassi, Steven M. Johnson, Hans E. Purkey et al. · Journal of the American Chemical Society · 2005 · 77 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17