De novo design and in vivo activity of conformationally restrained antimicrobial arylamide foldamers

Sungwook Choi, André K. Isaacs, Dylan J. Clements, +5

Proceedings of the National Academy of Sciences

Nontoxic Membrane‐Active Antimicrobial Arylamide Oligomers

Dahui Liu, Sungwook Choi, Bin Chen, +5

Angewandte Chemie International Edition

Arg-containing OligomerBioorganic ChemistryAntibiotic AdjuvantAntimicrobial ChemotherapyLead Compound +15

Nontoxic Membrane‐Active Antimicrobial Arylamide Oligomers

Dahui Liu, Sungwook Choi, Bin Chen, +5

Angewandte Chemie

Mechanisms of transthyretin cardiomyocyte toxicity inhibition by resveratrol analogs

Steve Bourgault, Sungwook Choi, Joel N. Buxbaum, +3

Biochemical and Biophysical Research Communications

MedicineLipid PeroxidationCardiovascular ToxicityPharmacologyResveratrol Analogs +1

Chemoselective small molecules that covalently modify one lysine in a non-enzyme protein in plasma

Sungwook Choi, Stephen Connelly, Natàlia Reixach, +2

Nature Chemical Biology

Protein ChemistryBiochemistryNatural SciencesChemoselective Small MoleculesEnzyme Catalysis +7

FOXO1 and FOXO3 transcription factors have unique functions in meniscus development and homeostasis during aging and osteoarthritis

Kwang Lee, Sungwook Choi, Tokio Matsuzaki, +5

Proceedings of the National Academy of Sciences

InflammationMeniscus DevelopmentMusculoskeletal ResearchFoxo FunctionAutoimmune Disease +13

Small-molecule inhibitors of integrin α ₂ β ₁ that prevent pathological thrombus formation via an allosteric mechanism

Meredith W. Miller, Sandeep Basra, Daniel W. Kulp, +8

Proceedings of the National Academy of Sciences

Antibacterial Mechanism of Action of Arylamide Foldamers

Bruk Mensa, Yong Ho Kim, Sungwook Choi, +3

Antimicrobial Agents and Chemotherapy

Arylamide FoldamersEngineeringBacteriologyEscherichia ColiAntimicrobial Chemotherapy +14

The Design and Evaluation of Heparin‐Binding Foldamers

Sungwook Choi, Dylan J. Clements, Vojislava Pophristic, +6

Angewandte Chemie International Edition

Protein AssemblyHeparin–small Molecule InteractionMolecular BiologyBlood LossPharmacotherapy +21

A Key Role for the Integrin α2β1 in Experimental and Developmental Angiogenesis

James D. San Antonio, Jason J. Zoeller, Kari Habursky, +8

American Journal Of Pathology

Signal TransductionAngiogenesisDevelopmental BiologyIntegrin α2β1Key Role +11