Concepedia

Improved specificity of TALE-based genome editing using an expanded RVD repertoire

Jeffrey C. Miller, Lei Zhang, Danny F. Xia, John J Campo, Irina Ankoudinova, Dmitry Guschin, Joshua Babiarz, Xiangdong Meng, Sarah J. Hinkley, Stephen C.-T. Lam,

Nature Methods · 2015 · 93 citations · 35 references

DOI

Concepts

References

35

DNA targeting specificity of RNA-guided Cas9 nucleases

Patrick D. Hsu, David A. Scott, Joshua A. Weinstein et al. · Nature Biotechnology · 2013 · 4.9K citations · Full text

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High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells

Yanfang Fu, Jennifer A Foden, Cyd Khayter et al. · Nature Biotechnology · 2013 · 3.3K citations · Full text

, , +16

Breaking the Code of DNA Binding Specificity of TAL-Type III Effectors

Jens Boch, Heidi Scholze, Sebastian Schornack et al. · Science · 2009 · 2.7K citations

, , +17

A TALE nuclease architecture for efficient genome editing

Jeffrey C. Miller, Siyuan Tan, Guijuan Qiao et al. · Nature Biotechnology · 2010 · 2.1K citations

, , +14

Efficient design and assembly of custom TALEN and other TAL effector-based constructs for DNA targeting

Tomáš Čermák, Erin Doyle, Michelle Christian et al. · Nucleic Acids Research · 2011 · 2.1K citations · Full text

, , +10