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Design and synthesis of orally-active and selective azaindane 5HT2c agonist for the treatment of obesity

Kevin K.‐C. Liu, Peter Cornelius, Terrell A. Patterson, Yuan Zeng, Stephanie Santucci, Elizabeth Tomlinson, Colleen P. Gibbons, Tristan S. Maurer, Ravi B. Marala, Janice A. Brown,

Bioorganic & Medicinal Chemistry Letters · 2009 · 22 citations · 4 references

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4

Leptin-independent hyperphagia and type 2 diabetes in mice with a mutated serotonin 5-HT2C receptor gene

Katsunori Nonogaki, Alison M. Strack, Mary F. Dallman et al. · Nature Medicine · 1998 · 463 citations

, , +16

5-HT 2C receptor activation decreases appetite and body weight in obese subjects

Peter A. Sargent, Ann L. Sharpley, Clare Williams et al. · Psychopharmacology · 1997 · 155 citations

, , +17

Nicotine attenuates DOI-induced head-twitch response in mice: implications for tourette syndrome

Yousef Tizabi, Lemuel T. Russell, Michael D. Johnson et al. · Progress in Neuro-Psychopharmacology and Biological Psychiatry · 2001 · 39 citations

, , +14

Biochemical basis for differences in metabolism-dependent genotoxicity by two diazinylpiperazine-based 5-HT2C receptor agonists

Amit S. Kalgutkar, Jonathan Bauman, Kim F. McClure et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 25 citations · Full text

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