Leptin-independent hyperphagia and type 2 diabetes in mice with a mutated serotonin 5-HT2C receptor gene

Adipose Expression of Tumor Necrosis Factor-α: Direct Role in Obesity-Linked Insulin Resistance

Gökhan S. Hotamışlıgil, Narinder S. Shargill, Bruce M. Spiegelman · Science · 1993 · 7.5K citations

Medicine, Endocrinology, Molecular Biology +17

Serum Immunoreactive-Leptin Concentrations in Normal-Weight and Obese Humans

Robert V. Considine, Madhur K. Sinha, Mark L. Heiman et al. · New England Journal of Medicine · 1996 · 6.3K citations

Medicine, Endocrinology, Nutritional Sciences +7

Weight-Reducing Effects of the Plasma Protein Encoded by the <i>obese</i> Gene

Jeffrey L. Halaas, K.S. Gajiwala, Margherita Maffei et al. · Science · 1995 · 4.5K citations

Medicine, Endocrinology, Nutritional Sciences +17

Effects of the <i>obese</i> Gene Product on Body Weight Regulation in <i>ob</i> / <i>ob</i> Mice

Mary Ann Pelleymounter, Mary Jane Cullen, Mary Baker et al. · Science · 1995 · 4K citations

Life Sciences, Biochemistry, Endocrinology +17

Leptin levels in human and rodent: Measurement of plasma leptin and ob RNA in obese and weight-reduced subjects

Margherita Maffei, Jeffrey L. Halaas, Éric Ravussin et al. · Nature Medicine · 1995 · 3.7K citations

Medicine, Endocrinology, Physiology +15